Brain Radiation Damage Reversed With Lithium
“From this, we conclude that lithium, given along the lines of this model, can help to heal the damage caused by radiotherapy, even long after it was caused,” says lead author Giulia Zanni, postdoctoral researcher at Columbia University and former PhD student in Klas Blomgren’s group at Karolinska Institutet.
#radiation #lithium #heal
Giulia Zanni, Shinobu Goto, Adamantia F. Fragopoulou, Giulia Gaudenzi, Vinogran Naidoo, Elena Di Martino, Gabriel Levy, Cecilia A. Dominguez, Olga Dethlefsen, Angel Cedazo-Minguez, Paula Merino-Serrais, Antonios Stamatakis, Ola Hermanson, Klas Blomgren. Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition. Molecular Psychiatry, 2019; DOI: 10.1038/s41380-019-0584-0