Mutant live attenuated Ebola virus immunizes non-human primates

Inoculation with an Ebola virus that has mutations in a protein called VP35 does not cause disease and elicits protection in monkeys, researchers show Sept. 17, 2019 in the journal Cell Reports. The findings suggest that the immune-evasion function of VP35 is a potential drug target, and it may be possible to develop a live attenuated Ebola virus vaccine in the future if precautions are taken to prevent reversion to virulence.

Source: Mutant live attenuated Ebola virus immunizes non-human primates

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