Finally, diabetic mice that were fed the nanoparticles for 5 days showed about 40% lower blood glucose levels compared to their starting amounts. Surprisingly, even 5 days after the treatment ended, the mice showed a 60% reduction in blood glucose compared to their starting levels.
Kaarunya Sampathkumar, Siriporn Riyajan, Chiew Kei Tan, Philip Demokritou, Nuannoi Chudapongse, Say Chye Joachim Loo. Small-Intestine-Specific Delivery of Antidiabetic Extracts from Withania coagulans Using Polysaccharide-Based Enteric-Coated Nanoparticles. ACS Omega, 2019; 4 (7): 12049 DOI: 10.1021/acsomega.9b00823